PF-Atlas › Clinical Trials › NCT00493194
Fibrosis in Renal Allografts
sirolimus · Phase 4
Registry ID
NCT00493194
Phase
Phase 4
Status
Unknown
Drug / intervention
sirolimus
Sponsor
University Hospital, Antwerp
Start
2005-05
Enrollment
100
Locations
3
About this trial
This prospective, randomized study, comparing sirolimus to cyclosporine in renal transplant recipients, has two major objectives: 1. -To determine the incidence and the degree of interstitialfibrosis and arteriosclerosis, as wel as the glomerular volume in protocol biopsies at 6 months in sirolimus-and in cyclosporine-treated renal allograft recipients, by means of quantitative computerized image analysis. * To determine the prognostic implication of these morphologic changes. 2. To study the expression of genes, involved in inflammation and fibrosis, in protocol biopsies at 6 months in sirolimus-and cyclosporine-treated renal allograft recipients.
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Medical disclaimer. This page summarizes public trial data for NCT00493194 for information only. It is not medical advice, an endorsement, or an offer to enroll. Confirm details on ClinicalTrials.gov and with a qualified physician.