PF-Atlas › Clinical Trials › NCT00188955
Pilot Study on the Use of Sirolimus to Treat Chronic Allograft Nephropathy in Children After Kidney Transplant
sirolimus · Phase 4
Registry ID
NCT00188955
Phase
Phase 4
Status
Completed
Drug / intervention
sirolimus
Sponsor
University of Manitoba
Start
2004-03
Enrollment
40
Locations
1
About this trial
The purpose of this study is to determine whether treatment with sirolimus, in combination with low-dose tacrolimus and prednisone, is effective for the treatment of chronic allograft nephropathy (progressive scarring) in children who have previously received a kidney transplant. This treatment is compared to the standard therapy which uses low-dose tacrolimus, mycophenolate mofetil and prednisons. This study is a pilot study that will determine whether treatment with sirolimus reduces or improves the rate of scarring seen on kidney biopsy of the transplanted kidney over time, compared to children who continue to be treated with mycophenolate mofetil.
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Medical disclaimer. This page summarizes public trial data for NCT00188955 for information only. It is not medical advice, an endorsement, or an offer to enroll. Confirm details on ClinicalTrials.gov and with a qualified physician.