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Исследования: Preprints (1331)
1331 публикаций в теме «Preprints», проиндексированных PF-Atlas из PubMed и мировых журналов.
- Multi-Omics Reprogramming Drives a Counterintuitive Reversal of Disease Susceptibility During Ageing · bioRxiv preprint · 2024
- Comparative Transcriptomic Analysis of ATRA-Resistant and ATRA-Sensitive APL Cell Lines Identifies LncRNA Biomarkers Associated with Drug Resistance · bioRxiv preprint · 2024
- A neurorecording toolkit for longitudinal assessments of transplanted human cortical organoids in vivo · bioRxiv preprint · 2024
- Reprogramming BCMA-Targeted CAR-T Cells through γ-Secretase Modulation Blocks Antigen Shedding and Extends CAR-T Longevity · bioRxiv preprint · 2024
- Top2a-dependent neuronal regulation of social behavior and persistent rescue of social deficit through PRC2-mediated epigenetic reprogramming · bioRxiv preprint · 2024
- Epigenetic regulation of TERRA transcription, R-loop formation, telomere integrity and metacyclogenesis by base J in Leishmania major. · bioRxiv preprint · 2024
- Reprogramming mRNA localization by targeted RNA-protein interference · bioRxiv preprint · 2024
- Suppression of YAP/TAZ molecular targets by epigenetic editing interferes with GBM growth and invasiveness · bioRxiv preprint · 2024
- Arginine synthesis pathway and ASS1 play a critical role in mRNA translation reprogramming and ICI resistance in cutaneous melanoma · bioRxiv preprint · 2024
- Wave-inspired MEW scaffolds for enhanced ligament tissue regeneration · bioRxiv preprint · 2024
- Novel clonal lineages of wheat stem rust in the Southern Cone of South America · bioRxiv preprint · 2024
- Inhibition of histone lysine demethylase restores learning and memory in aged mice · bioRxiv preprint · 2024
- Regional deficits in endogenous regeneration of olfactory sensory neuron axons in the mouse olfactory bulb · bioRxiv preprint · 2024
- Functional rescue of critical-size bone defect using molecular network analysis of axolotl limb regeneration. · bioRxiv preprint · 2024
- Mouse Cardiac Regeneration Database : a single-cell atlas of neonatal cardiac regeneration in mice · bioRxiv preprint · 2024
- Probing Critical Injury Thresholds for Maladaptive Epithelial Injury and Repair Processes with Photoresponsive Bioinspired Synthetic Basement Membrane · bioRxiv preprint · 2024
- Ergothioneine: Evaluation of a Novel Antioxidant for Targeting Ocular Oxidative Stress · bioRxiv preprint · 2024
- Lung derived extracellular vesicles have distinct pro-repair effects, depending on the age of their source tissue · bioRxiv preprint · 2024
- Biochemical and structural characterization of the RlaP family nucleotidyltransferase potentially involved in RNA repair · bioRxiv preprint · 2024
- PIF1, RAD54 and RDH54/TID1 promote residual double strand break repair during meiosis in the budding yeast, Saccharomyces cerevisiae · bioRxiv preprint · 2024
- Unraveling Genomic Signatures of lncRNA Expression in Zebrafish Caudal Fin Regeneration: Bridging Regenerative Potential and Positional Memory. · bioRxiv preprint · 2024
- A Minimal Physiological Model of Perceptual Suppression and Breakthrough in Visual Rivalry · bioRxiv preprint · 2024
- Novel estimation of memory in molecular dynamics with extended and comprehensive single-molecule tracking software: FreeTrace · bioRxiv preprint · 2024
- Immune Vascular intercellular signalling coordinates tissue plasticity during adult muscle repair in Drosophila. · bioRxiv preprint · 2024
- Human PMS1-dependent non-canonical mismatch repair converges with MBD4 to repair 5-methylcytosine deamination · bioRxiv preprint · 2024
- Aging disrupts tissue homeostasis and constrains blastema-mediated regeneration in the Cladonema medusa · bioRxiv preprint · 2024
- Novel Bacillus altitudinis endolysin targeting both Gram-positive and Gram-negative bacteria · bioRxiv preprint · 2024
- Transcranial direct current stimulation promotes myelin repair and plasticity in the mouse motor cortex · bioRxiv preprint · 2024
- Creation of Novel Methylating Conjugal Donor Strains for Genetically Recalcitrant Bacteria · bioRxiv preprint · 2024
- Ulacamten: A Novel, RLC-Targeting Cardiac Myosin Inhibitor for Potential Treatment of Cardiac Hypercontractility, Including HFpEF · bioRxiv preprint · 2024
- Full-length transcriptome atlas of Panax vietnamensis var. fuscidiscus reveals novel genes and alternative splicing in tissue-specific biosynthesis of ocotillol-type saponins · bioRxiv preprint · 2024
- A novel attention mechanism for noise-adaptive and robust segmentation of microtubules in microscopy images · bioRxiv preprint · 2024
- Novel devaluation methods to explore habits in humans · bioRxiv preprint · 2024
- PAK-family kinases promote cell fusion irreversibility by preventing cell wall repair · bioRxiv preprint · 2024
- Gene-environment interactions govern early regeneration in fir and beech: evidence from participatory provenance trials across Europe · bioRxiv preprint · 2024
- Investigating the repeatability and behavioral relationships of acuity, contrast sensitivity, form, and motion perception measurements using a novel tablet-based vision test tool · bioRxiv preprint · 2024
- Organellomics: AI-driven deep organellar phenotyping reveals novel ALS mechanisms in human neurons · bioRxiv preprint · 2024
- Proteomic stress response by a novel methanogen enriched from the Great Salt Lake · bioRxiv preprint · 2024
- Co-expression-based models improve eQTL predictions and highlightnovel transcriptome-wide genes associated with schizophrenia · bioRxiv preprint · 2024
- INPP5E interactome reveals novel connections to growth factor signaling · bioRxiv preprint · 2024
- The BOD1L subunit of the SETD1A complex sustains the expression of DNA damage repair genes despite restraining H3K4 trimethylation · bioRxiv preprint · 2024
- A novel proliferative candidate genes panel for idiopathic pulmonary fibrosis: insights from integrated bulk and single-cell RNA sequencing · bioRxiv preprint · 2024
- Modeling Somatic Second-Hit Mutations in Novel Mouse Models of Hereditary Hemorrhagic Telangiectasia · bioRxiv preprint · 2024
- A regenerative stem cell-derived matrix accelerates functional dermal wound repair in a diabetic model · bioRxiv preprint · 2024
- A novel Gorilla-derived oncolytic Adenovirus with natural selective replication in cancer cells · bioRxiv preprint · 2024
- Identifying a novel mechanism of L-leucine uptake in Mycobacterium tuberculosis using a chemical genomic approach · bioRxiv preprint · 2024
- Chronic exposure to low-concentration urban PM2.5 accelerates maladaptive repair after ischemic injury via mitochondrial dysfunction and lysosomal stress. · bioRxiv preprint · 2024
- A novel C57BL/6 mouse model for the study of severe Citrobacter rodentium infection · bioRxiv preprint · 2024
- De Novo Regeneration of Rete Ridges during Cetacean skin wound healing · bioRxiv preprint · 2024
- Mapping vascular plasticity in liver fibrogenesis identifies novel fibrosis-associated endothelial cells in early-stage liver disease · bioRxiv preprint · 2024
- Tolerance to Lung Infection in TWIK2 K+ Efflux Mediated Macrophage Trained Immunity · bioRxiv preprint · 2024
- GAS7 coordinates the activity of RAC1 and CDC42 to enhance macropinocytic surveillance and suppress motility in macrophages · bioRxiv preprint · 2024
- Single-mRNA imaging and modeling reveal coupled translation initiation and elongation rates · bioRxiv preprint · 2024
- Stability of orb mRNA in Drosophila ovaries is regulated by cis-regulatory elements in the three prime untranslated region and influences germ cell specification · bioRxiv preprint · 2024
- SLFN11 puts the brakes on Alternative lengthening of telomeres · bioRxiv preprint · 2024
- Inhibition of the macrophage demethylase LSD1 reverses Leishmania amazonensis-induced transcriptomic changes and causes a decrease in parasite load · bioRxiv preprint · 2024
- Loss of PAX6 alters the excitatory/inhibitory neuronal ratio in human cerebral organoids · bioRxiv preprint · 2024
- Iron deficiency drives metabolic adaptation of red pulp macrophages via FPN-SYK signaling and BCAA catabolism to enhance erythrophagocytosis · bioRxiv preprint · 2024
- The transcription of a single olfactory receptor per neuron is enforced by epigenetic silencing of their enhancers · bioRxiv preprint · 2024
- Ex vivo and in vivo CRISPR/Cas9 screenings identify the roles of protein N-glycosylation in regulating T-cell activation and functions · bioRxiv preprint · 2024
- Differential functions of multiple Wnts and receptors in cell polarity regulation in C. elegans · bioRxiv preprint · 2024
- Genome scale CRISPR screens identify actin capping proteins as key modulators of therapeutic responses to radiation and immunotherapy · bioRxiv preprint · 2024
- SF3A2 deacetylation at lysin 10 mitigates myocardial pathological remodeling by reprogramming cardiomyocyte metabolism · bioRxiv preprint · 2024
- Combinational adjuvants delivered by ink-jet potentiate naked mRNA vaccines for robust protection against infectious diseases · bioRxiv preprint · 2024
- A thermodynamic chromatin polymer model characterizes the epigenetic conditions for Hox collinearity. · bioRxiv preprint · 2024
- Macrophage-mediated epimorphosis in pig heart with right ventricular failure · bioRxiv preprint · 2024
- 3'to 5'translation of linear mRNAs? · bioRxiv preprint · 2024
- Lipid-mediated GPR32 signaling reprograms macrophage metabolism to impair anti-tuberculous immunity · bioRxiv preprint · 2024
- Parallel ZNF598 and GIGYF2 pathways mediate conserved collision-dependent mRNA decay with distinct endonucleolytic features · bioRxiv preprint · 2024
- Decoupled Representation Learning Improves Generalization in CRISPR Off-Target Prediction · bioRxiv preprint · 2024
- SPP1+macrophages promote the growth and metastasis of intrahepatic cholangiocarcinoma via OSM and THBS1 signaling · bioRxiv preprint · 2024
- Leveraging TNFR2 for antitumour immunity: T reg depletion and myeloid reprogramming versus T cell costimulation · bioRxiv preprint · 2024
- The Epigenetic Regulator Histone Demethylase KDM5A is Activated and Pathogenic in a Mouse Model of Heart Failure · bioRxiv preprint · 2024
- Astrocytic glycogenolysis gates Warburg-like metabolic reprogramming that promotes neuropathic pain chronification · bioRxiv preprint · 2024
- Protracted fate acquisition and epigenetic de-aging during induced neural stem cell conversion of human blood cells · bioRxiv preprint · 2024
- Wnt/β-catenin is required for proprioception by coordinating the multi-compartment development of muscle spindles · bioRxiv preprint · 2024
- Modeling Synaptic Maturation from Growth Cone to Synapse in Human Organoids · bioRxiv preprint · 2024
- Macrophage Cholesterol Homeostasis Underpins the role of Sertraline as an Adjunctive Agent in Tuberculosis Therapy. · bioRxiv preprint · 2024
- Investigating the skin response of Striped Catfish to acute ammonia stress reveals a potential exosome-based ammonia excretion system · bioRxiv preprint · 2024
- Comparative Landscape of Small RNAs in Tissue and Liquid Biopsies for Liver Transplant Outcomes · bioRxiv preprint · 2024
- Gene and cell line efficiency of CRISPR computed by tensor decomposition in genome-wide CRISPR-Cas9 knockout screens · bioRxiv preprint · 2024
- A Closed Computational - Experimental Loop Identifies Metabolic Collapse at the Root of Macrophage Dysfunction due to Zinc Dyshomeostasis · bioRxiv preprint · 2024
- Human adherent cortical organoids in a multiwell format · bioRxiv preprint · 2024
- Monocyte reprogramming by nociceptors impedes T cell-mediated tumor immunity · bioRxiv preprint · 2024
- Identification of an epigenetically and phenotypically distinct peritumoral glioblastoma cell population linked to inferior patient outcome · bioRxiv preprint · 2024
- Structural heterogeneity in mRNA-LNP subpopulations revealed by AF4-SAXS: implications for cargo loading and cell transfection · bioRxiv preprint · 2024
- Dynamic Epigenetic Changes During Antidepressant Pharmacotherapy in Major Depressive Disorder · bioRxiv preprint · 2024
- An Aggregation Prone Region in talin controls talin self-interactions to regulate integrin adhesion complex dynamics · bioRxiv preprint · 2024
- Inferences from epigenetic information in an ecological context: a case study of early-life environmental effects on DNA methylation in zebra finches · bioRxiv preprint · 2024
- Macrophage immunosenescence prolongs intraocular inflammation in aged mice via impaired induction of regulatory T cells · bioRxiv preprint · 2024
- Quantifying the oxygen preferences of bacterial communities using a metagenome-based approach · bioRxiv preprint · 2024
- T2T genome of the basal nematode Xiphinema index reveals major adaptive events associated to plant parasitism and epigenetic regulation · bioRxiv preprint · 2024
- Drosophila TRAPPC8-Rab1 module regulates retrograde trafficking of Wingless and Evi/Wntless · bioRxiv preprint · 2024
- REGULATION OF COLONIC MACROPHAGES AND TYPE-17 AND REGULATORY T CELLS IN DSS-COLITIS BY IBD-ASSOCIATED TRANSCRIPTION FACTOR, CREM · bioRxiv preprint · 2024
- Murine CMV Infection Unmasks Macrophage-Driven Inflammatory Cardiomyopathy in Pkp2, but not in Ttn Mutant Mice · bioRxiv preprint · 2024
- The REFLEX system enables in vivo identification of perivascular angiogenic macrophages in the heart · bioRxiv preprint · 2024
- Cell-autonomous thermogenesis of macrophage alters its antibacterial function · bioRxiv preprint · 2024
- MtDNA heteroplasmy controls tumor immune reprogramming through mitochondrial translation · bioRxiv preprint · 2024
- Large mRNA language foundation modeling with NUWA for unified sequence perception and generation · bioRxiv preprint · 2024
- TREM2 agonist antibody rebuilds the resident synovial macrophage lining barrier in rheumatoid arthritis · bioRxiv preprint · 2024
- Crosstalk between Stromal cells and Macrophages Shapes Host Immunity to Mycobacteria · bioRxiv preprint · 2024
- Distinct DNA-binding syntax and chromatin remodeling capacities of bHLH transcription factors in cell differentiation, reprogramming and cancer · bioRxiv preprint · 2024
- 2-Deoxyglucose dendrimer-enabled niclosamide delivery to FRβ-expressing macrophages alleviates endometriosis progression and associated hyperalgesia · bioRxiv preprint · 2024
- ML-guided robotic microinjection of single neurons in human brain organoids · bioRxiv preprint · 2024
- Polarization Increases Nuclear Stiffness in Macrophages Despite Reduction in Lamin A/C Levels · bioRxiv preprint · 2024
- In situ mutational screening and CRISPR interference define apterous cis-regulatory inputs during compartment boundary formation · bioRxiv preprint · 2024
- Reprogramming CAR T-Cells with designed bioPROTACs · bioRxiv preprint · 2024
- SHAP-Guided CpG Selection with Ensemble Learning for Epigenetic Age Prediction · bioRxiv preprint · 2024
- Female iPSC X-chromosome inactivation erosion and its transcriptomic effects during CRISPR gene editing and neural differentiation · bioRxiv preprint · 2024
- Proteomic Screening Identifies HNRNPA2B1 as an Epigenetic Repressor of Epstein-Barr Virus Reactivation · bioRxiv preprint · 2024
- Single-cell Analysis of Paired FFPE Placentas Reveals Trophoblast Reprogramming and Immune Dysregulation in Chronic Villitis of Unknown Etiology · bioRxiv preprint · 2024
- Noncanonical P gene mRNA editing in Cedar virus generates a V-like protein that is required for efficient virion production · bioRxiv preprint · 2024
- Acquisition and extinction of drug-context memories are linked to distinct epigenetic and transcriptional mechanisms in the mouse dentate gyrus · bioRxiv preprint · 2024
- Temporal Mapping of Radiation-Induced Neural Injury and Mitigation in Human Cortical Organoids · bioRxiv preprint · 2024
- Co-evolution of Oncogenic KRAS Signaling and LILRBhigh Macrophages Drives Pancreatic Cancer Recurrence · bioRxiv preprint · 2024
- Epigenetic Silencing of Carotid Body TRPM7 Attenuates Hypertension in Obese Mice · bioRxiv preprint · 2024
- Human enterochromaffin cells and apical-out intestinal organoids as models for human sapovirus infection · bioRxiv preprint · 2024
- Optimized iMAP CRISPR Perturbation Illuminates Context-Specific Functions of RNA Modification Factors · bioRxiv preprint · 2024
- Neuronal Population Effects of Ketamine on Human Brain Organoids · bioRxiv preprint · 2024
- A genome-wide CRISPR-Cas9 screen identifies TGN46 as a host determinant for H-1PV susceptibility in pancreatic adenocarcinoma. · bioRxiv preprint · 2024
- mRNA-Protein Coordination is Contextualized by Metastatic Biological Phenotypes · bioRxiv preprint · 2024
- Functional Separation of mRNA Domains Coordinates Pluripotent Cell Behavior · bioRxiv preprint · 2024
- Metabolic reprogramming and partial acquisition of cancer stem cell-like phenotype in human umbilical cord-mesenchymal stem cells under hypoxia · bioRxiv preprint · 2024
- Reconstitution of the Spinal Cord Injury Microenvironment in Adult Neural Stem Cell-Derived Organoids · bioRxiv preprint · 2024
- Leveraging unbiased LC-MS analysis to identify histone post-translational modifications associated with age-related decline of learning and memory · bioRxiv preprint · 2024
- TaExpA6, VRT-A2 and TaGW2 genes differentially affect grain weight, grain number and yield of wheat through their physiological determinants · bioRxiv preprint · 2024
- eIF2Bϵ phosphorylation activates integrated stress response-mediated protein translation and links stress signalling toamyloidogenesis in Alzheimer's disease · bioRxiv preprint · 2024
- Artemis Regulates Homology-Independent Prime Editing for Enhanced Genomic Insertions · bioRxiv preprint · 2024
- Multimodal cell lineage reconstruction in the hindbrain reveals a link between progenitor origin and activity patterning · bioRxiv preprint · 2024
- Dynamic alterations of DNA methylation and transcriptome in adaptation to and recovery from the space environment · bioRxiv preprint · 2024
- Curved Axially Scanned Light-Sheet Microscopy · bioRxiv preprint · 2024
- Downregulation of Trpv4 and Klf2 in brain microvessels is associated with the progression of neurovascular dysfunction and cognitive impairment in a model of heart failure with preserved ejection fraction. · bioRxiv preprint · 2024
- Comprehensive multi-omics profiling of a healthy human cohort · bioRxiv preprint · 2024
- Rare longevity-associated variants, including a reduced-function mutation in cGAS, identified in multigenerational long-lived families · bioRxiv preprint · 2024
- Identification of cell types associated with 14 brain phenotypes from more than 10 million single cells · bioRxiv preprint · 2024
- Multi-modal, multi-species, and multi-task latent-space model for decoding level of consciousness · bioRxiv preprint · 2024
- Molecular Surveillance Identifies Evidence of Getah Virus in Mosquito Vectors in Alabama, USA · bioRxiv preprint · 2024
- Network-based analysis reveals microRNA regulation of oncogenic pathways in SOX10-depleted uveal melanoma · bioRxiv preprint · 2024
- Automated detection and quantification of two-spotted spider mite life stages using computer vision for high-throughput in vitro assays · bioRxiv preprint · 2024
- Intracellular growth of Chlamydia trachomatis leads to global histone hypermethylation by impairing demethylation · bioRxiv preprint · 2024
- A Forebrain Hub for Cautious Actions via the Midbrain · bioRxiv preprint · 2024
- Graph embeddings for identifying symmetries in connectomes · bioRxiv preprint · 2024
- O-GlcNAc Transferase Regulates GABAergic Synapse Organization and Receptor Composition. · bioRxiv preprint · 2024
- CBP-IDRs regulate acetylation and gene expression. · bioRxiv preprint · 2024
- Genotype-phenotype correlations and de novo induction of cancer stem cells in Wilms tumor initiation. · bioRxiv preprint · 2024
- Pore-size dynamics control complex volume swelling in pyroptosis. · bioRxiv preprint · 2024
- mmContext: an open framework for multimodal contrastive learning of omics and text data · bioRxiv preprint · 2024
- Critical spatial separation at the scale of V1 receptive fields determines motion segmentation · bioRxiv preprint · 2024
- Finite-State Likelihood: an Approximation for Genome Phylogeny Inference based on Generalized Gene Contents · bioRxiv preprint · 2024
- EMCF ecosystem: Towards pretrained foundation model for electron microscopy image analysis · bioRxiv preprint · 2024
- p16INK4A expression induces paracrine senescence via small extracellular vesicles · bioRxiv preprint · 2024
- IsoNet2 determines cellular structures at submolecular resolution without averaging · bioRxiv preprint · 2024
- Classifying Calcium Imaging Dynamics with Deep Learning: Multi-Frequency Analysis through Quantile-Based Time-Series Network Representations · bioRxiv preprint · 2024
- Alveolar Type II Cell-derived MMP1high basal cells promote destructive microcysts in idiopathic pulmonary fibrosis. · bioRxiv preprint · 2024
- A behavioral architecture for realistic simulations of Drosophila larva locomotion and foraging · bioRxiv preprint · 2024
- Global molecular landscape of early MASLD progression in obesity · bioRxiv preprint · 2024
- Understanding the physiological behaviour of disc cells in an in vitro imitation of the healthy and degenerated disc niche · bioRxiv preprint · 2024
- Obesity reprograms adipose extracellular vesicles to induce muscle atrophy via miR-150-5p-mediated transcriptional silencing · bioRxiv preprint · 2024
- Adaptive Responses Directed by CREB Control Epithelial-Mesenchymal Plasticity in Cancer · bioRxiv preprint · 2024
- Plasticity of extrachromosomal DNA segregation during drug adaptation · bioRxiv preprint · 2024
- Non-apoptotic death of the C. elegans linker cell is primed by MYRF-1 activation of pqn-41/polyQ · bioRxiv preprint · 2024
- Cholesterol Remodeling by CH25h Rewires IFITM3 Trafficking and Secretion Without Enhancing Antiviral Restriction · bioRxiv preprint · 2024
- Small Molecule Degradation of the microRNA-21 Precursor Rescues Pathogenic Pathways in Cellular Models of Fibrosis · bioRxiv preprint · 2024
- High-throughput glycan array screening reveals rhamnogalacturonan-I as a ligand for Arabidopsis leucine-rich repeat receptor kinases · bioRxiv preprint · 2024
- Natural scene and object perception based on statistical image features: psychophysics and EEG · bioRxiv preprint · 2024
- Anesthesia Lowers Spatial Frequency Preference in the Primary Visual Cortex · bioRxiv preprint · 2024
- The Powered Simplest Walking Model Explains the Different Vertical Ground Reaction Force Amplitudes at Elevated Walking Speeds · bioRxiv preprint · 2024
- Learning Invariant Graph Representations for Cox Survival Modeling under Distribution Shifts · bioRxiv preprint · 2024
- Phase Behavior of TDP-43 and hnRNP H1: From Soluble and Aggregated States to Liquid-Like Droplets · bioRxiv preprint · 2024
- Electrical control of the transduction channels' gating force in sensory hair cells. · bioRxiv preprint · 2024
- Conserved principles of spatial biology define tumor heterogeneity and response to immunotherapy · bioRxiv preprint · 2024
- Aging promotes escape from X chromosome inactivation in human tissues · bioRxiv preprint · 2024
- Perturbational single-cell profiling of patient tumors defines lineage- and context-specific programs of innate immune resistance · bioRxiv preprint · 2024
- Visual features underlying neural selectivity for natural stimuli · bioRxiv preprint · 2024
- A high-quality genome assembly and integrative data portal for the Mesoamerican black bean · bioRxiv preprint · 2024
- Top-down control of sustained attention by the medial prefrontal cortex - locus coeruleus circuit during the rodent continuous performance task · bioRxiv preprint · 2024
- P/Q-type voltage-gated calcium channels regulate calcium signaling and developmental myelination in oligodendrocyte lineage cells · bioRxiv preprint · 2024
- Presynaptic GABAB autoreceptors suppress neurotransmitter release during repetitive stimulation via the Gβγ-SNARE pathway. · bioRxiv preprint · 2024
- Awake infant fMRI: Insights from more than 750 scanning sessions · bioRxiv preprint · 2024
- Dorsolateral striatal acetylcholine reorganizes neural ensembles to anticipate threat · bioRxiv preprint · 2024
- Birthdate aligns vestibular sensory neurons with central and motor partners across a sensorimotor reflex circuit for gaze stabilization · bioRxiv preprint · 2024
- Mucin-type O-glycans regulate proteoglycan stability and chondrocyte maturation · bioRxiv preprint · 2024
- Dot1L licenses DNA demethylation to establish regulatory T cell identity · bioRxiv preprint · 2024
- Human-specific lncRNAs contributed critically to human evolution by distinctly regulating gene expression · bioRxiv preprint · 2024
- The expression level of CACNA1C-encoded CaV1.2 is a tipping point between promotion and inhibition of dendritic growth in neurons · bioRxiv preprint · 2024
- Investigation of CD36 interactome provides insights into multimolecular complexes necessary for anti-angiogenic signalling · bioRxiv preprint · 2024
- Superabundant microRNAs are transcribed from human rDNA spacer promoters insulated by CTCF · bioRxiv preprint · 2024
- Determinants of Process-Level Parameters Governing MS2 Virus-Like Particle Reassembly · bioRxiv preprint · 2024
- Distinct Temporal Patterns of Human Neural Firing in the Subthalamic Nucleus During Speech and Orofacial Movement · bioRxiv preprint · 2024
- A Unified Mechanism for Depth Perception and Figure-Ground Organization · bioRxiv preprint · 2024
- Foundation model reveals the shared organization of transcription and topologically associating domains · bioRxiv preprint · 2024
- Modelling motion-induced signal corruption in steady-state diffusion MRI · bioRxiv preprint · 2024
- MatClassRSA v2 release: A MATLAB toolbox for M/EEG classification, proximity matrix construction, and visualization · bioRxiv preprint · 2024
- Circadian Rhythms of Whole-Body Metabolite Abundance in Drosophila are Largely Driven by Time of Feeding · bioRxiv preprint · 2024
- Molecular interactome of HNRNPU reveals regulatory networks in neuronal differentiation and DNA methylation · bioRxiv preprint · 2024
- Transient SUMOylation Inhibition In Human Pre-adipocytes Stably Imprints a Transcriptional Beiging Fate · bioRxiv preprint · 2024
- Tissue Specific Requirement for the Inv Oncogene CBFB::MYH11 in Acute Myeloid Leukemia · bioRxiv preprint · 2024
- On Copiotrophy and Temperature: Controls on Microbial Maximum Growth Rate Versus Translation Rate Optimization · bioRxiv preprint · 2024
- The cell cycle variant in multiciliated cells incorporates 2 centriole biogenesis cycles · bioRxiv preprint · 2024
- Neuroligin-2 is ubiquitinated by Nedd4l to control developmental astrocyte morphogenesis. · bioRxiv preprint · 2024
- Alzheimer disease risk variant rs11218343 determines functional expression of SORL1 in microglia · bioRxiv preprint · 2024
- Trans-regulation of heterochromatin underlies genetic variation in 3D genome contacts · bioRxiv preprint · 2024
- Calorie restriction leads to degradation of mutant uromodulin and ameliorates inflammation and fibrosis in UMOD-related kidney disease · bioRxiv preprint · 2024
- CyTOF-based profiling of circulating tumor cells predicts aggressiveness and therapy response in SCLC liquid biopsies at a personalized level · bioRxiv preprint · 2024
- Refining liquid chromatography conditions across platforms to democratize single-cell proteomics · bioRxiv preprint · 2024
- Knowledge-guided machine-learning and reverse screening combined method to predict cancer cell line responses to cytotoxic molecules · bioRxiv preprint · 2024
- Characterizing common loss-of-function genes and their potential utility in assessing population variability and chemical susceptibility · bioRxiv preprint · 2024
- Science-wide mapping and ranking of institutions based on affiliated authors · bioRxiv preprint · 2024
- Ectopic engraftment of nociceptive neurons derived from hPSCs for pain relief and joint homeostasis · bioRxiv preprint · 2024
- Prion shedding is reduced by chronic wasting disease vaccination · bioRxiv preprint · 2024
- Integrating brain structure and function for the neurobiology and genetics of language · bioRxiv preprint · 2024
- LIVN: A testbed for learning to interact with in vitro neural networks · bioRxiv preprint · 2024
- RPE pseudopods maintain photoreceptor outer segment renewal despite subretinal space expansion in Adam9 knockout mice · bioRxiv preprint · 2024
- Mapping of critical prosodic and phonetic networks in post-stroke apraxia of speech · bioRxiv preprint · 2024
- Lysergic acid diethylamide pretreatment prolongs brain-stimulation induced neural activity · bioRxiv preprint · 2024
- Genetic Associations with Longevity in a Calabrian Cohort: A Genome-Wide Study · bioRxiv preprint · 2024
- Senescent CD8+ T Effector Memory Cells are Functionally Impaired, Enriched in Aging and Disease, and a Barrier to Immunotherapy · bioRxiv preprint · 2024
- Gestational inhibition of CSF1R signaling using PLX5622 drives musculoskeletal changes in postnatal offspring · bioRxiv preprint · 2024
- Nuclear N-Glycosylation Redefines the Glycoscape and Directs Cell Identity · bioRxiv preprint · 2024
- Age-related sensory dysfunction reconfigures the spinal circuitry for touch, itch and pain · bioRxiv preprint · 2024
- Visual input drives diverse ER calcium signals in neurons in vivo · bioRxiv preprint · 2024
- Fast and slow learning mediated by distinct climbing fiber signals · bioRxiv preprint · 2024
- Single-cell perturbations reveal adaptive, stimulus-dependent recurrence in visual cortex · bioRxiv preprint · 2024
- What sets the mutation rate of a cell type in an animal species? · bioRxiv preprint · 2024
- MultiGAI: Global Attention-Based Integration of Single-Cell Multi-Omics with Batch Effects Correction · bioRxiv preprint · 2024
- Evolutionary Decoding of the Bacillus subtilis Secretome: Insights from Pan-Genomics and Deep Learning · bioRxiv preprint · 2024
- Coevolution of neoplastic and non-neoplastic reactive astrocyte states converges on mesenchymal-like and injury-response programs during murine glioblastoma progression and post-radiotherapy recurrence · bioRxiv preprint · 2024
- Susceptibility of Glucose Regulation to Social Isolation · bioRxiv preprint · 2024
- Systematic overexpression reveals a conserved spectrum of harmful and beneficial amino acid homorepeats shaped by evolution · bioRxiv preprint · 2024
- Ephaptic coupling can explain variability in neural activity · bioRxiv preprint · 2024
- Myeloid cells contribute to bystander CD8 T cell accumulation in metabolic-associated steatohepatitis and are sufficient for fibrosis · bioRxiv preprint · 2024
- Resilience to cardiac aging in Greenland shark Somniosus microcephalus · bioRxiv preprint · 2024
- Age-related MICOS Complex Dysregulation Impairs Mitochondrial 3D Architecture and Metabolic Homeostasis in the Liver · bioRxiv preprint · 2024
- Impact of Socioeconomic Status on Amygdala and Hippocampus Subdivisions in Children and Adolescents · bioRxiv preprint · 2024
- A ligand/receptor trafficking clock governs self-renewal and abscission dynamics in pluripotent stem cells · bioRxiv preprint · 2024
- Quantitative Network Classification with CLaSSiNet Reveals Nanoscale Organizational Principles of the Membrane Skeleton · bioRxiv preprint · 2024
- Cardiolipin Remodeling as a Regulatory Switch in Osteogenesis: Insights from Multimodal Metabolic Imaging and Molecular Profiling · bioRxiv preprint · 2024
- Accessory subunits of PRC2 mimic H3K27me3 to restrict the spread of Polycomb domains · bioRxiv preprint · 2024
- A Thalamocortical Cell-Adhesion Code Primes Sensory Cortical Specification · bioRxiv preprint · 2024
- Adoptive cell therapy using T cell receptors equipped with ICOS yields durable anti-tumor response · bioRxiv preprint · 2024
- Systematic Analysis of Network-driven Adaptive Resistance to CDK4/6 and Estrogen Receptor Inhibition using Meta-Dynamic Network Modelling · bioRxiv preprint · 2024
- Hierarchical buffering of cellular RNA polymerase II pools maintains transcriptional homeostasis · bioRxiv preprint · 2024
- Phenotypic Screening Coupled with AI-Driven Target Deconvolution Identifies α-Terthienyl as a Dual DPP-IV/HSD17β13 Modulator with Efficacy in a Mouse Model of MASLD · bioRxiv preprint · 2024
- Maternal Influenza A Virus Infection Induces Antiviral and Immune Dysregulation in the Placenta and Fetus Without Vertical Transmission · bioRxiv preprint · 2024
- Identification and Functional Characterization of Isoflavone Synthase Gene Family in Pea : The Entry Point to Pisatin Biosynthesis · bioRxiv preprint · 2024
- ZNF865 Regulates Back Pain via Cell Senescence and DNA Damage Mechanisms · bioRxiv preprint · 2024
- FLEXTAG: A Small and Self-renewable Protein Labeling System for Anti-fading Multi-color Super-resolution Imaging · bioRxiv preprint · 2024
- AWmeta empowers adaptively-weighted transcriptomic meta-analysis · bioRxiv preprint · 2024
- The aging transcriptome: a condition-dependent response to a deteriorating soma · bioRxiv preprint · 2024
- Eph-Ephrin Tetramerization Inhibitors Target Bidirectional Signaling to Combat Pain and Addiction · bioRxiv preprint · 2024
- Segmental copy number amplifications are more stable than aneuploidies in the absence of selection · bioRxiv preprint · 2024
- SuSiE 2.0: improved methods and implementations for genetic fine-mapping and phenotype prediction · bioRxiv preprint · 2024
- Daple-FLT3 gene fusion requires the coiled-coil domain for maximal activation and pericentrosomal localization · bioRxiv preprint · 2024
- Integrative Analysis of Spatial Transcriptome and Connectome by SpaCon · bioRxiv preprint · 2024
- Chromosome-length genome assembly of Uta stansburiana and gene expression data reveal fast pace-of-life comes with environmental stability · bioRxiv preprint · 2024
- An auditory "low road" for threat in humans sensitive to fast temporal cues · bioRxiv preprint · 2024
- Conditional-longitudinal brain growth charts detect MRI changes with birth weight and psychopathology · bioRxiv preprint · 2024
- Optimal parameters for measuring multiband auditory brainstem responses to continuous speech · bioRxiv preprint · 2024
- Adoptive Transfer of ILC2s into the Brain Reveals Tumor Homing in Glioblastoma: A Proof-of-Concept for Cellular Therapy · bioRxiv preprint · 2024
- SpaceTrooper: a quality control framework for imaging-basedspatial omics data · bioRxiv preprint · 2024
- Real-time monitoring of pediatric high-grade glioma invasion using organotypic brain cultures reveals a developmentally dependent sensitivity · bioRxiv preprint · 2024
- MECP2 Duplication Uncouples Mitochondrial and Purine Metabolism During neuronal maturation · bioRxiv preprint · 2024
- Uncovering Shared and Tissue-Specific Molecular Adaptations to Intermittent Fasting in Liver, Brain, and Muscle · bioRxiv preprint · 2024
- Astrocytic glycolysis attenuates mitochondrial efficiency to preserve cognition · bioRxiv preprint · 2024
- Single-cell chiral symmetry breaking under confinement · bioRxiv preprint · 2024
- A Theory of Thalamocortical Loops in Evidence Accumulation and Decision-Making · bioRxiv preprint · 2024
- Differential Cerebral White Matter Tract Alterations in Generalized Anxiety Disorder Revealed by Ultra-High Field 7T Diffusion-Weighted Imaging · bioRxiv preprint · 2024
- Resting-State fMRI and the Risk of Overinterpretation: Noise, Mechanisms, and a Missing Rosetta Stone · bioRxiv preprint · 2024
- Aging increases ovarian cancer growth, metastasis and immunosuppression that can be alleviated by inhibiting hedgehog signaling · bioRxiv preprint · 2024
- Anthropogenic habitats shape gut microbiome composition in Southern Indian bats · bioRxiv preprint · 2024
- Multimodal spatial transcriptomics determines repeat expansion, huntingtin aggregation, and selective cortical neuron loss in Huntington Disease · bioRxiv preprint · 2024
- Transcriptomic and functional characterization indicate sexual dimorphism of discrete circadian neuron subtypes · bioRxiv preprint · 2024
- Semenogelin-1 Inhibition of Mouse Sperm Hyperactivation Reveals Two Functional Domains Modulating CatSper Channel · bioRxiv preprint · 2024
- Cytoplasmic flow induced by a rotating wire in living cells: Magnetic rotational spectroscopy and finite element simulations · bioRxiv preprint · 2024
- Dynamic regulation of protein homeostasis underlies acquired thermotolerance in Arabidopsis · bioRxiv preprint · 2024
- The geometry of cooperation: decoding microbial interactions · bioRxiv preprint · 2024
- On-target mutations confer resistance to WRN helicase inhibitors in Microsatellite Unstable Cancer Cells. · bioRxiv preprint · 2024
- Improving Cryo-EM Optimization Robustness with an Optimal Transport Loss Function for Noisy Images · bioRxiv preprint · 2024
- GLP-1R Agonism Directly Improves the Pumping Capacity of Murine Collecting Lymphatic Vessels · bioRxiv preprint · 2024
- SuperFocus enables whole-slide cell-level spatial omics from spot-based measurements and histology across modalities · bioRxiv preprint · 2024
- Integrating 12 Spatial and Single Cell Technologies to Characterise Tumour Neighbourhoods and Cellular Interactions in three Skin Cancer Types · bioRxiv preprint · 2024
- Surprising regulatory plasticity for the conserved HOG pathway in diverse Saccharomyces cerevisiae strains · bioRxiv preprint · 2024
- Cell-in-Water: measurements using Optical Photothermal Infrared spectroscopy · bioRxiv preprint · 2024
- Biomimetic graphitic carbon nitride nanoparticles enable multiscale biomodulation · bioRxiv preprint · 2024
- An upstream secondary DNA motif within the IL3 insulator CTCF binding site is required for enhancer-blocking insulator activity · bioRxiv preprint · 2024
- Spatially resolved translational dysregulation in Grin2a+/- mouse model of schizophrenia · bioRxiv preprint · 2024
- Anaesthesia selectively decouples signal propagation from responsivity in the fronto-parietal loop · bioRxiv preprint · 2024
- GenoME: a MoE-based generative model for individualized, multimodal prediction and perturbation of genomic profiles · bioRxiv preprint · 2024
- Genome editing of the flavanone 3-hydroxylase gene produces a green Perilla line with elevated luteolin accumulation · bioRxiv preprint · 2024
- Envelope analysis as a tool for identifying epileptic EEG patterns during the sleep-wake cycle in rats · bioRxiv preprint · 2024
- Immune gene co-expression networks are constrained by a non-linear topology spectral relationship · bioRxiv preprint · 2024
- Mathematical modeling of light chain aggregation and cardiac damage in AL amyloidosis · bioRxiv preprint · 2024
- Genome-wide Identification of the Laccase Gene Family in White Jute : Potential Targets for Lignin Engineering in Bast Fiber · bioRxiv preprint · 2024
- APE1 Coordinates Its Disordered Region and Metal Cofactors to Drive Genome Surveillance · bioRxiv preprint · 2024
- An annotated chromosome-level genome assembly ofthe Adzuki bean borer Ostrinia scapulalis · bioRxiv preprint · 2024
- Intrinsic DNA sequence determinants and tissue-specific regulation of human replication origins · bioRxiv preprint · 2024
- Structural basis for non-AUG translation regulation by 5MPs · bioRxiv preprint · 2024
- Virus-Host Interaction Gets Lousy: P1vir Phage Development Upon Impaired RNA Global Regulation in Escherichia coli Δhfq Mutant Cells · bioRxiv preprint · 2024
- The interplay between autophagy and the carbon/nitrogen ratio as key modulator of the auxin-dependent chloronema-caulonema developmental transition in Physcomitrium patens. · bioRxiv preprint · 2024
- Connections of early visual areas with posterior parietal and temporal cortex in galagos, a strepsirrhine primate · bioRxiv preprint · 2024
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