מחקר: Gene Editing (33)
33 מאמרים בנושא Gene Editing, מאונדקסים על ידי PF-Atlas מ-PubMed וכתבי עת עולמיים.
- Macrophage metabolic reprogramming in organ transplantation: mechanisms, transplant outcomes, and therapeutic implications. · Frontiers in cellular and infection microbiology · 2026
- Double-stranded DNA donors and CRISPR-Cas9 for universal correction of mutations causing cystic fibrosis in human airway cells. · Molecular therapy. Nucleic acids · 2026
- Comparison of Prime Editing and CRISPR-Cas Mediated HDR in Correcting CFTR-F508del Mutation in Patient iPSC-Derived Airway Basal Cells. · International journal of molecular sciences · 2026
- Functional correction of the untreatable CFTR 1717-1G>A mutation through mRNA- and sgRNA-optimized base editing. · Science translational medicine · 2026
- CRISPR-Cas9 genome editing in the parental iPSC line PCIi033-A to introduce the homozygous mutation p.F508del in the CFTR gene. · Stem cell research · 2026
- Ablation of PKCα Phosphorylation by CRISPR-Cas9 Base Editing Rescues Heart Failure. · Circulation research · 2026
- Genome editing of Spp1 by inhalable CRISPR/Cas9 formulation for treating pulmonary fibrosis. · Journal of controlled release : official journal of the Controlled Release Society · 2026
- Human Embryonic Stem Cell-Derived Immunity-And-Matrix-Regulatory Cells Attenuate Pulmonary Fibrosis via MMP1-Mediated Collagen Degradation. · Cell proliferation · 2026
- Critical role for the TGF-β1/mTORC1 signaling axis in defining the transcriptional identity of CTHRC1 pathologic fibroblasts. · Science advances · 2026
- Pulmonary delivery of gene-loaded lipid nanoparticles for targeting TGF-β signaling in idiopathic pulmonary fibrosis. · Nanomedicine (London, England) · 2026
- Base editing and nanoparticle transfection of airway cell types essential for treatment of cystic fibrosis. · JCI insight · 2026
- Precision A3G base editors for disease modeling and correction. · Molecular therapy : the journal of the American Society of Gene Therapy · 2026
- CRISPR for cystic fibrosis: Advances and insights from a systematic review. · Molecular therapy : the journal of the American Society of Gene Therapy · 2025
- Genome-Wide CRISPR Screen for Unveiling Radiosensitive and Radioresistant Genes. · Journal of visualized experiments : JoVE · 2025
- Gene Editing for Cystic Fibrosis: Advances and Prospects of CRISPR-Cas9 Therapy. · Cell biology international · 2025
- Detection of pre-existing immunity to bacterial Cas9 proteins in people with cystic fibrosis. · ImmunoHorizons · 2025
- Prime Editing Modification with FEN1 Improves F508del Variant Editing in the CFTR Gene in Airway Basal Cells. · International journal of molecular sciences · 2025
- Lung tissue-optimized gene editing in human cystic fibrosis models following topical application of lipid nanoparticles. · Journal of controlled release : official journal of the Controlled Release Society · 2025
- Selection of Optimal pegRNAs to Enhance Efficiency of Prime Editing in AT-Rich Genome Regions. · Biochemistry. Biokhimiia · 2025
- Cystic fibrosis therapy: from symptoms to the cause of the disease. · Vavilovskii zhurnal genetiki i selektsii · 2025
- Cutting-Edge Advances in Cystic Fibrosis: From Gene Therapy to Personalized Medicine and Holistic Management. · Genes · 2025
- Prime editing-installed suppressor tRNAs for disease-agnostic genome editing. · Nature · 2025
- Pediatric Liver Diseases: Next-Generation Therapies. · Clinics in liver disease · 2025
- PDZ-Binding Kinase, a Novel Regulator of Vascular Remodeling in Pulmonary Arterial Hypertension. · Circulation · 2024
- Bone-marrow-homing lipid nanoparticles for genome editing in diseased and malignant haematopoietic stem cells. · Nature nanotechnology · 2024
- Lung SORT LNPs enable precise homology-directed repair mediated CRISPR/Cas genome correction in cystic fibrosis models · Nature Communications · 2023
- Targeted epigenetic silencing of UCHL1 expression suppresses collagen-1 production in human lung epithelial cells. · Epigenetics · 2023
- CAGE sequencing reveals CFTR-dependent dysregulation of type I IFN signaling in activated cystic fibrosis macrophages. · Science advances · 2023
- Genome-engineering technologies for modeling and treatment of cystic fibrosis. · Advances in medical sciences · 2023
- Potential of helper-dependent Adenoviral vectors in CRISPR-cas9-mediated lung gene therapy. · Cell & bioscience · 2021
- CRISPR/Cas9 gene editing therapies for cystic fibrosis. · Expert opinion on biological therapy · 2021
- Hermansky-Pudlak Syndrome and Lung Disease: Pathogenesis and Therapeutics. · Frontiers in pharmacology · 2021
- New Directions in Pulmonary Gene Therapy. · Human gene therapy · 2020
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