PF-AtlasClinical Trials › NCT07169253

Prognostic Score Comparison in IPF and HP

GAP Index · Not specified

Registry ID
NCT07169253
Phase
Not specified
Status
Completed
Drug / intervention
GAP Index
Sponsor
Saglik Bilimleri Universitesi
Start
2022-10-01
Enrollment
143
Locations
1

About this trial

The goal of this retrospective observational study is to evaluate and compare the prognostic value of GAP, ILD-GAP, and CPI scoring systems in patients diagnosed with interstitial lung diseases (ILDs), specifically Idiopathic Pulmonary Fibrosis (IPF), fibrotic Hypersensitivity Pneumonitis, and non-fibrotic Hypersensitivity Pneumonitis. The main questions it aims to answer are: * Can GAP, ILD-GAP, and CPI scores accurately predict prognosis in IPF, fibrotic HP, and non-fibrotic HP patients? * Are there differences in prognostic performance of these models across different ILD subtypes? Researchers will compare the prognostic utility of GAP, ILD-GAP, and CPI scores between IPF, fibrotic HP, and non-fibrotic HP groups to see if one scoring system offers superior predictive power. Participants: * Adults aged ≥18 years * Diagnosed between October 2011 and October 2021 at the University of Health Sciences Yedikule Chest Diseases and Thoracic Surgery Training and Research Hospital * 143 patients in total (IPF: 45, fibrotic HP: 26, non-fibrotic HP: 72) Participants' data will include: * Clinical and demographic characteristics * Symptom duration * Radiologic imaging findings * Pulmonary function test (PFT) results * Bronchoalveolar lavage (BAL) findings * Histopathological diagnoses Scoring systems will be calculated using standardized formulas as follows: * GAP (Gender, Age, Physiology) * ILD-GAP (modified GAP for CTD-ILDs) * CPI (Composite Physiologic Index = 91 - \[0.65 × %DLCO\] - \[0.53 × %FVC\] + \[0.34 × %FEV1\])

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Medical disclaimer. This page summarizes public trial data for NCT07169253 for information only. It is not medical advice, an endorsement, or an offer to enroll. Confirm details on ClinicalTrials.gov and with a qualified physician.