PF-Atlas › Clinical Trials › NCT04580368

Testing Drug Efficacy in Cystic Fibrosis Through N-of-1 Trials

CFTR Modulators · Not specified

Registry ID
NCT04580368
Phase
Not specified
Status
Recruiting
Drug / intervention
CFTR Modulators
Sponsor
Children's Hospital Medical Center, Cincinnati
Start
2021-05-01
Enrollment
50
Locations
1

About this trial

The purpose of this study is to validate and utilize a personalized medicine approach to identify potential treatments with current FDA approved CFTR modifiers for non-approved CF gene mutations. The study will perform ex vivo testing of CFTR function and current marketed CFTR modulating drugs on expanded nasal cells at Cincinnati Children's Human Nasal Epithelium (HNE) Core Laboratory. The results will be confirmed and translated into bedside care through an N of 1 trial to determine effectiveness of treatment.

View NCT04580368 on ClinicalTrials.gov →

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Medical disclaimer. This page summarizes public trial data for NCT04580368 for information only. It is not medical advice, an endorsement, or an offer to enroll. Confirm details on ClinicalTrials.gov and with a qualified physician.