iPSC-Derived AEC2 Transplant
Idiopathic Pulmonary Fibrosis · Autologous iPSC-AEC2s replace depleted stem cell pool in prepared niche
Mechanism
Autologous iPSC-AEC2s replace depleted stem cell pool in prepared niche
Development stage
Preclinical
Evidence level
Level 3 (Preclinical)
Developer
BU/BMC
Overview
Kotton lab gold standard iPSC-to-AEC2 protocol. Engraftment ~5% currently. Niche preparation is key.
Explore related
Medical disclaimer. This page summarizes research about iPSC-Derived AEC2 Transplant for information only. It is not medical advice. Verify approval status and evidence with the FDA and a pulmonologist.