CD49a
Idiopathic Pulmonary Fibrosis · Adoptive transfer of lung-resident memory T cells reverses established fibrosis
Mechanism
Adoptive transfer of lung-resident memory T cells reverses established fibrosis
Development stage
Preclinical
Evidence level
Level 3 (Preclinical)
Developer
Multiple
Overview
bioRxiv 2024: adoptive transfer of CD49a+ tissue resident memory cells reversed pulmonary fibrosis in mice. Novel approach — uses the lung own immune memory system rather than engineered cells. Potential for autologous therapy.
Explore related
Medical disclaimer. This page summarizes research about CD49a for information only. It is not medical advice. Verify approval status and evidence with the FDA and a pulmonologist.