PF-Atlas › Clinical Trials › NCT01094704
Durability of Hypertonic Saline for Enhancing Mucociliary Clearance in Cystic Fibrosis
sodium chloride · Phase 1
Registry ID
NCT01094704
Phase
Phase 1
Status
Completed
Drug / intervention
sodium chloride (7%)
Sponsor
University of North Carolina, Chapel Hill
Start
2009-11
Enrollment
16
Locations
2
About this trial
Direct measurement of mucociliary and cough clearance (MCC/CC) has been used as a biomarker in cystic fibrosis (CF). Additional knowledge of the performance of this biomarker is needed to inform exploratory clinical trial design in support of programs to develop new inhaled therapies for CF. We hypothesize that MCC/CC measurements can be used to determine the durability of action of agents like hypertonic saline (HS) which increase epithelial lining fluid height.
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Medical disclaimer. This page summarizes public trial data for NCT01094704 for information only. It is not medical advice, an endorsement, or an offer to enroll. Confirm details on ClinicalTrials.gov and with a qualified physician.